AustralieFrV1, Main, Exploration, bibRecord, 005947

Rheumatic heart disease

Identifieur interne : 005947 ( Main/Exploration ); précédent : 005946; suivant : 005948

Rheumatic heart disease

Auteurs : Eloi Marijon [France] ; Mariana Mirabel [France, Royaume-Uni] ; David S. Celermajer [Australie] ; Xavier Jouven [France, Royaume-Uni]

Source :

Lancet : (British edition) [ 0140-6736 ] ; 2012.

RBID : Pascal:12-0137539

Descripteurs français

Pascal (Inist)
- Rhumatisme, Médecine, Cardiopathie.
Wicri :
- topic : Médecine.

English descriptors

KwdEn :
- Heart disease, Medicine, Rheumatism.

Abstract

Rheumatic heart disease, often neglected by media and policy makers, is a major burden in developing countries where it causes most of the cardiovascular morbidity and mortality in young people, leading to about 250000 deaths per year worldwide. The disease results from an abnormal autoimmune response to a group A streptococcal infection in a genetically susceptible host. Acute rheumatic fever-the precursor to rheumatic heart disease-can affect different organs and lead to irreversible valve damage and heart failure. Although penicillin is effective in the prevention of the disease, treatment of advanced stages uses up a vast amount of resources, which makes disease management especially challenging in emerging nations. Guidelines have therefore emphasised antibiotic prophylaxis against recurrent episodes of acute rheumatic fever, which seems feasible and cost effective. Early detection and targeted treatment might be possible if populations at risk for rheumatic heart disease in endemic areas are screened. In this setting, active surveillance with echocardiography-based screening might become very important.

Affiliations:

Links toward previous steps (curation, corpus...)

to stream PascalFrancis, to step Corpus: 001532
to stream PascalFrancis, to step Curation: 004980
to stream PascalFrancis, to step Checkpoint: 000E00
to stream Main, to step Merge: 005C35
to stream Main, to step Curation: 005947

Le document en format XML

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<front><div type="abstract" xml:lang="en">Rheumatic heart disease, often neglected by media and policy makers, is a major burden in developing countries where it causes most of the cardiovascular morbidity and mortality in young people, leading to about 250000 deaths per year worldwide. The disease results from an abnormal autoimmune response to a group A streptococcal infection in a genetically susceptible host. Acute rheumatic fever-the precursor to rheumatic heart disease-can affect different organs and lead to irreversible valve damage and heart failure. Although penicillin is effective in the prevention of the disease, treatment of advanced stages uses up a vast amount of resources, which makes disease management especially challenging in emerging nations. Guidelines have therefore emphasised antibiotic prophylaxis against recurrent episodes of acute rheumatic fever, which seems feasible and cost effective. Early detection and targeted treatment might be possible if populations at risk for rheumatic heart disease in endemic areas are screened. In this setting, active surveillance with echocardiography-based screening might become very important.</div>
</front>
</TEI>
<affiliations><list><country><li>Australie</li>
<li>France</li>
<li>Royaume-Uni</li>
</country>
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<tree><country name="France"><region name="Île-de-France"><name sortKey="Marijon, Eloi" sort="Marijon, Eloi" uniqKey="Marijon E" first="Eloi" last="Marijon">Eloi Marijon</name>
</region>
<name sortKey="Jouven, Xavier" sort="Jouven, Xavier" uniqKey="Jouven X" first="Xavier" last="Jouven">Xavier Jouven</name>
<name sortKey="Jouven, Xavier" sort="Jouven, Xavier" uniqKey="Jouven X" first="Xavier" last="Jouven">Xavier Jouven</name>
<name sortKey="Jouven, Xavier" sort="Jouven, Xavier" uniqKey="Jouven X" first="Xavier" last="Jouven">Xavier Jouven</name>
<name sortKey="Marijon, Eloi" sort="Marijon, Eloi" uniqKey="Marijon E" first="Eloi" last="Marijon">Eloi Marijon</name>
<name sortKey="Marijon, Eloi" sort="Marijon, Eloi" uniqKey="Marijon E" first="Eloi" last="Marijon">Eloi Marijon</name>
<name sortKey="Mirabel, Mariana" sort="Mirabel, Mariana" uniqKey="Mirabel M" first="Mariana" last="Mirabel">Mariana Mirabel</name>
<name sortKey="Mirabel, Mariana" sort="Mirabel, Mariana" uniqKey="Mirabel M" first="Mariana" last="Mirabel">Mariana Mirabel</name>
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<country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Mirabel, Mariana" sort="Mirabel, Mariana" uniqKey="Mirabel M" first="Mariana" last="Mirabel">Mariana Mirabel</name>
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<name sortKey="Jouven, Xavier" sort="Jouven, Xavier" uniqKey="Jouven X" first="Xavier" last="Jouven">Xavier Jouven</name>
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<country name="Australie"><region name="Nouvelle-Galles du Sud"><name sortKey="Celermajer, David S" sort="Celermajer, David S" uniqKey="Celermajer D" first="David S." last="Celermajer">David S. Celermajer</name>
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</record>

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	Serveur d'exploration sur les relations entre la France et l'Australie
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Rheumatic heart disease

Rheumatic heart disease

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri